The article analyses the climatogenic factors and how they influence the transport system (network) of the Republic of Moldova. The following climatogenetic factors were analysed: dynamic, physical-geographic, etc. as well as some specific climatic elements as the temperature of the air, cloud amount, humidity, direction and speed of the wind. As a conclusion it can be mentioned that when tracing the terrestrial transport system it is necessary to take into consideration the climatic factors which directly influence this field of human activity.